Hydroxychloroquine induced lung cancer suppression by enhancing chemo-sensitization and promoting the transition of M2-TAMs to M1-like macrophages.
Identifieur interne : 000C32 ( Main/Exploration ); précédent : 000C31; suivant : 000C33Hydroxychloroquine induced lung cancer suppression by enhancing chemo-sensitization and promoting the transition of M2-TAMs to M1-like macrophages.
Auteurs : Yong Li [République populaire de Chine] ; Fengjun Cao [République populaire de Chine] ; Mingxing Li [République populaire de Chine] ; Pindong Li [République populaire de Chine] ; Yuandong Yu [République populaire de Chine] ; Longchao Xiang [République populaire de Chine] ; Tao Xu [République populaire de Chine] ; Jinhua Lei [République populaire de Chine] ; Yun Yan Tai [République populaire de Chine] ; Jianyong Zhu [République populaire de Chine] ; Bingbing Yang [République populaire de Chine] ; Yingpin Jiang [République populaire de Chine] ; Xiufang Zhang [République populaire de Chine] ; Long Duo [République populaire de Chine] ; Ping Chen [République populaire de Chine] ; Xiongjie Yu [République populaire de Chine]Source :
- Journal of experimental & clinical cancer research : CR [ 1756-9966 ] ; 2018.
Descripteurs français
- KwdFr :
- Animaux, Carcinome pulmonaire non à petites cellules (anatomopathologie), Carcinome pulmonaire non à petites cellules (traitement médicamenteux), Cellules A549, Concentration en ions d'hydrogène, Humains, Hydroxychloroquine (administration et posologie), Hydroxychloroquine (pharmacologie), Lignée cellulaire tumorale, Lymphocytes T CD8+ (), Lymphocytes T CD8+ (métabolisme), Lysosomes (), Macrophages (), Macrophages (anatomopathologie), Microenvironnement tumoral (), Prolifération cellulaire (), Régulation de l'expression des gènes tumoraux (), Souris, Survie cellulaire (), Synergie des médicaments, Tests d'activité antitumorale sur modèle de xénogreffe, Tumeurs du poumon (anatomopathologie), Tumeurs du poumon (traitement médicamenteux).
- MESH :
- administration et posologie : Hydroxychloroquine.
- anatomopathologie : Carcinome pulmonaire non à petites cellules, Macrophages, Tumeurs du poumon.
- métabolisme : Lymphocytes T CD8+.
- pharmacologie : Hydroxychloroquine.
- traitement médicamenteux : Carcinome pulmonaire non à petites cellules, Tumeurs du poumon.
- Animaux, Cellules A549, Concentration en ions d'hydrogène, Humains, Lignée cellulaire tumorale, Lymphocytes T CD8+, Lysosomes, Macrophages, Microenvironnement tumoral, Prolifération cellulaire, Régulation de l'expression des gènes tumoraux, Souris, Survie cellulaire, Synergie des médicaments, Tests d'activité antitumorale sur modèle de xénogreffe.
English descriptors
- KwdEn :
- A549 Cells, ATP Binding Cassette Transporter, Subfamily B (metabolism), Animals, CD8-Positive T-Lymphocytes (drug effects), CD8-Positive T-Lymphocytes (metabolism), Carcinoma, Non-Small-Cell Lung (drug therapy), Carcinoma, Non-Small-Cell Lung (pathology), Cell Line, Tumor, Cell Proliferation (drug effects), Cell Survival (drug effects), Drug Synergism, Gene Expression Regulation, Neoplastic (drug effects), Humans, Hydrogen-Ion Concentration, Hydroxychloroquine (administration & dosage), Hydroxychloroquine (pharmacology), Lung Neoplasms (drug therapy), Lung Neoplasms (pathology), Lysosomes (chemistry), Lysosomes (drug effects), Macrophages (drug effects), Macrophages (pathology), Mice, Tumor Microenvironment (drug effects), Xenograft Model Antitumor Assays.
- MESH :
- chemical , administration & dosage : Hydroxychloroquine.
- chemical , metabolism : ATP Binding Cassette Transporter, Subfamily B.
- chemistry : Lysosomes.
- drug effects : CD8-Positive T-Lymphocytes, Cell Proliferation, Cell Survival, Gene Expression Regulation, Neoplastic, Lysosomes, Macrophages, Tumor Microenvironment.
- drug therapy : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms.
- metabolism : CD8-Positive T-Lymphocytes.
- pathology : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Macrophages.
- chemical , pharmacology : Hydroxychloroquine.
- A549 Cells, Animals, Cell Line, Tumor, Drug Synergism, Humans, Hydrogen-Ion Concentration, Mice, Xenograft Model Antitumor Assays.
Abstract
Lysosome-associated agents have been implicated as possible chemo-sensitizers and immune regulators for cancer chemotherapy. We investigated the potential roles and mechanisms of hydroxychloroquine (HCQ) in combination with chemotherapy in lung cancer treatment.
DOI: 10.1186/s13046-018-0938-5
PubMed: 30373678
Affiliations:
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Le document en format XML
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xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Xiang, Longchao" sort="Xiang, Longchao" uniqKey="Xiang L" first="Longchao" last="Xiang">Longchao Xiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Xu, Tao" sort="Xu, Tao" uniqKey="Xu T" first="Tao" last="Xu">Tao Xu</name><affiliation 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sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Cao, Fengjun" sort="Cao, Fengjun" uniqKey="Cao F" first="Fengjun" last="Cao">Fengjun Cao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Li, Mingxing" sort="Li, Mingxing" uniqKey="Li M" first="Mingxing" last="Li">Mingxing Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030</wicri:regionArea><wicri:noRegion>430030</wicri:noRegion></affiliation></author><author><name sortKey="Li, Pindong" sort="Li, Pindong" uniqKey="Li P" first="Pindong" last="Li">Pindong Li</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation></author><author><name sortKey="Yu, Yuandong" sort="Yu, Yuandong" uniqKey="Yu Y" first="Yuandong" last="Yu">Yuandong Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Xiang, Longchao" sort="Xiang, Longchao" uniqKey="Xiang L" first="Longchao" last="Xiang">Longchao Xiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Xu, Tao" sort="Xu, Tao" uniqKey="Xu T" first="Tao" last="Xu">Tao Xu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Lei, Jinhua" sort="Lei, Jinhua" uniqKey="Lei J" first="Jinhua" last="Lei">Jinhua Lei</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Tai, Yun Yan" sort="Tai, Yun Yan" uniqKey="Tai Y" first="Yun Yan" last="Tai">Yun Yan Tai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Jianyong" sort="Zhu, Jianyong" uniqKey="Zhu J" first="Jianyong" last="Zhu">Jianyong Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Medicine, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Medicine, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000</wicri:regionArea><wicri:noRegion>442000</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Bingbing" sort="Yang, Bingbing" uniqKey="Yang B" first="Bingbing" last="Yang">Bingbing Yang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Yingpin" sort="Jiang, Yingpin" uniqKey="Jiang Y" first="Yingpin" last="Jiang">Yingpin Jiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiufang" sort="Zhang, Xiufang" uniqKey="Zhang X" first="Xiufang" last="Zhang">Xiufang Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Duo, Long" sort="Duo, Long" uniqKey="Duo L" first="Long" last="Duo">Long Duo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Ping" sort="Chen, Ping" uniqKey="Chen P" first="Ping" last="Chen">Ping Chen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Yu, Xiongjie" sort="Yu, Xiongjie" uniqKey="Yu X" first="Xiongjie" last="Yu">Xiongjie Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei, China. yuxiongjie2002@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang middle Rd, Shiyan, 442000, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of experimental & clinical cancer research : CR</title><idno type="eISSN">1756-9966</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>A549 Cells</term><term>ATP Binding Cassette Transporter, Subfamily B (metabolism)</term><term>Animals</term><term>CD8-Positive T-Lymphocytes (drug effects)</term><term>CD8-Positive T-Lymphocytes (metabolism)</term><term>Carcinoma, Non-Small-Cell Lung (drug therapy)</term><term>Carcinoma, Non-Small-Cell Lung (pathology)</term><term>Cell Line, Tumor</term><term>Cell Proliferation (drug effects)</term><term>Cell Survival (drug effects)</term><term>Drug Synergism</term><term>Gene Expression Regulation, Neoplastic (drug effects)</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Hydroxychloroquine (administration & dosage)</term><term>Hydroxychloroquine (pharmacology)</term><term>Lung Neoplasms (drug therapy)</term><term>Lung Neoplasms (pathology)</term><term>Lysosomes (chemistry)</term><term>Lysosomes (drug effects)</term><term>Macrophages (drug effects)</term><term>Macrophages (pathology)</term><term>Mice</term><term>Tumor Microenvironment (drug effects)</term><term>Xenograft Model Antitumor Assays</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Carcinome pulmonaire non à petites cellules (anatomopathologie)</term><term>Carcinome pulmonaire non à petites cellules (traitement médicamenteux)</term><term>Cellules A549</term><term>Concentration en ions d'hydrogène</term><term>Humains</term><term>Hydroxychloroquine (administration et posologie)</term><term>Hydroxychloroquine (pharmacologie)</term><term>Lignée cellulaire tumorale</term><term>Lymphocytes T CD8+ ()</term><term>Lymphocytes T CD8+ (métabolisme)</term><term>Lysosomes ()</term><term>Macrophages ()</term><term>Macrophages (anatomopathologie)</term><term>Microenvironnement tumoral ()</term><term>Prolifération cellulaire ()</term><term>Régulation de l'expression des gènes tumoraux ()</term><term>Souris</term><term>Survie cellulaire ()</term><term>Synergie des médicaments</term><term>Tests d'activité antitumorale sur modèle de xénogreffe</term><term>Tumeurs du poumon (anatomopathologie)</term><term>Tumeurs du poumon (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>ATP Binding Cassette Transporter, Subfamily B</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome pulmonaire non à petites cellules</term><term>Macrophages</term><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Lysosomes</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>CD8-Positive T-Lymphocytes</term><term>Cell Proliferation</term><term>Cell Survival</term><term>Gene Expression Regulation, Neoplastic</term><term>Lysosomes</term><term>Macrophages</term><term>Tumor Microenvironment</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Carcinoma, Non-Small-Cell Lung</term><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>CD8-Positive T-Lymphocytes</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Lymphocytes T CD8+</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Carcinoma, Non-Small-Cell Lung</term><term>Lung Neoplasms</term><term>Macrophages</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Carcinome pulmonaire non à petites cellules</term><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" xml:lang="en"><term>A549 Cells</term><term>Animals</term><term>Cell Line, Tumor</term><term>Drug Synergism</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Mice</term><term>Xenograft Model Antitumor Assays</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Cellules A549</term><term>Concentration en ions d'hydrogène</term><term>Humains</term><term>Lignée cellulaire tumorale</term><term>Lymphocytes T CD8+</term><term>Lysosomes</term><term>Macrophages</term><term>Microenvironnement tumoral</term><term>Prolifération cellulaire</term><term>Régulation de l'expression des gènes tumoraux</term><term>Souris</term><term>Survie cellulaire</term><term>Synergie des médicaments</term><term>Tests d'activité antitumorale sur modèle de xénogreffe</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lysosome-associated agents have been implicated as possible chemo-sensitizers and immune regulators for cancer chemotherapy. We investigated the potential roles and mechanisms of hydroxychloroquine (HCQ) in combination with chemotherapy in lung cancer treatment.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name></noRegion><name sortKey="Cao, Fengjun" sort="Cao, Fengjun" uniqKey="Cao F" first="Fengjun" last="Cao">Fengjun Cao</name><name sortKey="Chen, Ping" sort="Chen, Ping" uniqKey="Chen P" first="Ping" last="Chen">Ping Chen</name><name sortKey="Duo, Long" sort="Duo, Long" uniqKey="Duo L" first="Long" last="Duo">Long Duo</name><name sortKey="Jiang, Yingpin" sort="Jiang, Yingpin" uniqKey="Jiang Y" first="Yingpin" last="Jiang">Yingpin Jiang</name><name sortKey="Lei, Jinhua" sort="Lei, Jinhua" uniqKey="Lei J" first="Jinhua" last="Lei">Jinhua Lei</name><name sortKey="Li, Mingxing" sort="Li, Mingxing" uniqKey="Li M" first="Mingxing" last="Li">Mingxing Li</name><name sortKey="Li, Pindong" sort="Li, Pindong" uniqKey="Li P" first="Pindong" last="Li">Pindong Li</name><name sortKey="Tai, Yun Yan" sort="Tai, Yun Yan" uniqKey="Tai Y" first="Yun Yan" last="Tai">Yun Yan Tai</name><name sortKey="Xiang, Longchao" sort="Xiang, Longchao" uniqKey="Xiang L" first="Longchao" last="Xiang">Longchao Xiang</name><name sortKey="Xu, Tao" sort="Xu, Tao" uniqKey="Xu T" first="Tao" last="Xu">Tao Xu</name><name sortKey="Yang, Bingbing" sort="Yang, Bingbing" uniqKey="Yang B" first="Bingbing" last="Yang">Bingbing Yang</name><name sortKey="Yu, Xiongjie" sort="Yu, Xiongjie" uniqKey="Yu X" first="Xiongjie" last="Yu">Xiongjie Yu</name><name sortKey="Yu, Yuandong" sort="Yu, Yuandong" uniqKey="Yu Y" first="Yuandong" last="Yu">Yuandong Yu</name><name sortKey="Zhang, Xiufang" sort="Zhang, Xiufang" uniqKey="Zhang X" first="Xiufang" last="Zhang">Xiufang Zhang</name><name sortKey="Zhu, Jianyong" sort="Zhu, Jianyong" uniqKey="Zhu J" first="Jianyong" last="Zhu">Jianyong Zhu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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